RNA Details
Disease Name
cardiomegaly
Tissue
heart
RNA Symbol
mir-221
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
NA
Target
NA
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-221/222 Family Counteracts Myocardial Fibrosis in Pressure Overload-Induced Heart Failure
Year
2018
Function
Heart failure-associated downregulation of the miRNA-221/222 family enables profibrotic signaling in the pressure-overloaded heart.